BU72
Product Specifications
CAS Number
173265-76-4
Target
Opioid Receptor
Related Pathways
GPCR/G Protein|||Neuroscience|||Endocrinology/Hormones
Bioactivity
BU72 is a potent, long-lasting agonist for ? and ? opioid receptors, with partial agonistic activity at the ? opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively) . It provides strong, enduring analgesic effects primarily mediated through ? opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.
Smiles
O(C)[C@@]12[C@@]3([C@@]45C(CC1(C)[C@H](N3)C6=CC=CC=C6)([C@@](CC=7C4=CC(O)=CC7)(N(C)CC5)[H])C=C2)[H]
Molecular Formula
C28H32N2O2
Molecular Weight
428.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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