BCX-3607
Product Specifications
CAS Number
885684-79-7
Target
Others
Related Pathways
Others
Bioactivity
BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor with an IC50 of 4 nM. By inhibiting the TF-FVIIa complex, it effectively blocks the extrinsic coagulation pathway and significantly prolongs prothrombin time (PT) . BCX-3607 exhibits higher selectivity for TF-FVIIa over other serine proteases like thrombin and FXa. It reduces thrombus weight and inflammation, offering dual anti-thrombotic and anti-inflammatory effects. BCX-3607 is applicable in research on thrombosis-related diseases.
Smiles
O=C(O)C1=CC(=CC=C1C=2C=CC(C=C)=CC2CNC3=NC=C(C=C3)C(=N)N)C(=O)NCC(C)C
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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