Tezusomant

Product Specifications

CAS Number

2802416-72-2

Target

GHSR

Related Pathways

GPCR/G Protein

Bioactivity

Tezusomant is an antagonist of the growth hormone receptor (growth hormone receptor) . It is being investigated for potential use in conditions like acromegaly, which are caused by excessive secretion of growth hormone.

Smiles

O=C1[C@@]2(CC=3C=4C(N(C3)CC(=O)NCCCC[C@](N(C)C(=O)[C@H](CC5=CC=C(C(O)=O)C=C5)NC(=O)CSC[C@@H](C(NCCCC[C@H](NC(CC[C@H](NC(CC[C@H](NC(CCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)C(O)=O)=O)C(N)=O)=O)NC(=O)[C@H]([C@H](C)C)NC(=O)C(C)(C)NC(=O)[C@H](CC=6C=7C(NC6)=CC=C(O)C7)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC8=CC=C(C(O)=O)C=C8)N1)(C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H]([C@H](C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N2)[H])=CC=CC4)[H]