Anti-inflammatory agent 102
Product Specifications
CAS Number
3053104-47-2
Target
MAP3K, MAPK, NF-κB, p38 MAPK, Reactive Oxygen Species, Interleukin, NO Synthase
Related Pathways
Immunology/Inflammation, NF-κB, MAPK, Metabolism
Bioactivity
Anti-inflammatory agent 102 (Compound 11a) is an orally effective anti-inflammatory compound. It exerts its effects by inhibiting the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. This agent displays significant anti-inflammatory activity by suppressing the release of NO, ROS, and inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Anti-inflammatory agent 102 is applicable in research concerning inflammatory diseases, including ulcerative colitis (UC) .
Smiles
O=C1N(C2=NC=CC=C2)CCN1C3=CC(Cl)=C(OC)C=C3OC
Molecular Formula
C16H16ClN3O3
Molecular Weight
333.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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