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Keap1-Nrf2-IN-28

Product Specifications

Target

Nrf2

Related Pathways

Immunology/Inflammation

Bioactivity

Keap1-Nrf2-IN-28 (SG16) is an orally active inhibitor of Keap1-Nrf2. It demonstrates antioxidant properties and upregulates the expression of Nrf2, HO-1, GCLM, and Akr1c1. Additionally, Keap1-Nrf2-IN-28 can mitigate acute liver injury induced by APAP.

Smiles

O=C1C=C(OC2=CC(=CC=C12)NS(=O)(=O)C3=CC=C(F)C=C3)C=4C=CC(OC)=CC4

Molecular Formula

C22H16FNO5S

Molecular Weight

425.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/351433519160885342/T207165

CAS Number

3075750-60-3

Available Sizes

Curated Selection

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