Keap1-Nrf2-IN-28
Product Specifications
CAS Number
3075750-60-3
Target
Nrf2
Related Pathways
Immunology/Inflammation
Bioactivity
Keap1-Nrf2-IN-28 (SG16) is an orally active inhibitor of Keap1-Nrf2. It demonstrates antioxidant properties and upregulates the expression of Nrf2, HO-1, GCLM, and Akr1c1. Additionally, Keap1-Nrf2-IN-28 can mitigate acute liver injury induced by APAP.
Smiles
O=C1C=C(OC2=CC(=CC=C12)NS(=O)(=O)C3=CC=C(F)C=C3)C=4C=CC(OC)=CC4
Molecular Formula
C22H16FNO5S
Molecular Weight
425.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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