AKR1C3-IN-15
Product Specifications
CAS Number
3059671-44-9
Target
Reductase, Apoptosis
Related Pathways
Metabolism, Endocrinology/Hormones, Apoptosis
Bioactivity
AKR1C3-IN-15 (compound 30) is an effective and selective AKR1C3 inhibitor with an IC50 value of 5 nM. It enhances Sorafenib-induced ROS production, promotes apoptosis, and restores sensitivity to Sorafenib in hepatocellular carcinoma (HCC) models, as demonstrated in both in vitro and in vivo studies.
Smiles
O=C(O)C1=CC=C(C=C1)CN(C(=O)C2=CC=3C=CC(F)=CC3OC2)C
Molecular Formula
C19H16FNO4
Molecular Weight
341.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
032713 200 µL
C14orf126, CT (C14orf126, Probable D-tyrosyl-tRNA (Tyr) deacylase 2)
Sign In for Pricing
View Details 222439-01 50 µL
EP4 (Prostanoid EP4 Receptor, PGE Receptor. EP4 subtype, PTGER4, PTGER2, EP4, EP4R, MGC126583) discontinued
Sign In for Pricing
View Details 222439-02 100 µL
EP4 (Prostanoid EP4 Receptor, PGE Receptor. EP4 subtype, PTGER4, PTGER2, EP4, EP4R, MGC126583) discontinued
Sign In for Pricing
View Details 
VAng-Lsx4373-inquire Inquire
Recombinant Bordetella Parapertussis htpG Protein (aa 1-635)
Sign In for Pricing
View Details NBP1-41070AF350 0.1 mL
Rabbit Polyclonal DCP2 Antibody [Alexa Fluor 350]
Sign In for Pricing
View Details 
MBS688140-01 0.5 mg
Donkey anti-Mouse IgG (H&L) - F(ab)'2 fragment, HRP Conjugate, min x w/bovine, chicken, goat, guinea pig, hamster, horse, human, rabbit, rat or sheep IgG
Sign In for Pricing
View Details