CDK2-IN-45
Product Specifications
Target
Apoptosis, CDK
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Bioactivity
CDK2-IN-45 is a CDK2 inhibitor with an IC50 value of 0.64 μM. It effectively inhibits the proliferation of DU-145 and PC-3 cell lines, with IC50 values of 2.20 μM and 4.17 μM, respectively. Additionally, CDK2-IN-45 induces G0/G1 phase cell cycle arrest and apoptosis. It is utilized in prostate cancer research.
Smiles
ClC(C=C1)=CC=C1C2=CC=NC3=C(C(NC4=CC=CC=C4)=NN32)C5=NC6=CC=CC=C6S5
Molecular Formula
C25H16ClN5S
Molecular Weight
453.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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