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PSSI-51

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

PSSI-51 is an orally active inhibitor of succinyl-CoA:3-ketoacid CoA transferase (SCOT) with selectivity for peripheral tissues. It effectively inhibits SCOT activity in peripheral tissues such as muscle and kidney, without affecting SCOT activity in brain tissue. By inhibiting SCOT, PSSI-51 reduces ketone body oxidation, thereby improving obesity-related hyperglycemia. It shows potential for research in type 2 diabetes (T2D) and in addressing obesity-related metabolic disorders.

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FC1=CC=C(C(C2=CC=C(F)C=C2)N3CCN(CCCN4C(C(C=CC=C5)=C5C4=O)=O)CC3)C=C1.Cl.Cl

Molecular Formula

C28H29Cl2F2N3O2

Molecular Weight

548.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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