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MDAR-IN-1

Product Specifications

Target

Cholinesterase (ChE), iGluR

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Bioactivity

MDAR IN-1 (Compound 5m) is a brain-penetrant acetylcholinesterase (AChE) inhibitor and an antagonist of the NMDAR receptor GluN1/GluN2B subtype. It effectively inhibits AChE activity, enhances cholinergic neurotransmission, and blocks NMDAR to reduce excitotoxicity. MDAR IN-1 shows potential for Alzheimer’s disease research.

Smiles

NC1=C2C(CCCC2)=NC3=CC=C(C4=CC(C)=CS4)C=C31

Molecular Formula

C18H18N2S

Molecular Weight

294.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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