MS7710
Product Specifications
Target
HCN Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
MS7710 is a brain-penetrant inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. It reduces Ih current by inhibiting HCN channels, thereby decreasing the activity of dopamine neurons in the ventral tegmental area (VTA) . MS7710 effectively improves social interaction deficits and reward-related cognitive flexibility in mouse models of chronic social defeat stress (CSDS) and shows promise for depression research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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