CB039
Product Specifications
CAS Number
3056259-55-0
Target
Molecular Glues
Related Pathways
PROTAC
Bioactivity
CB039 is a selective degrader targeting RBM39 (RNA binding motif protein 39) . It facilitates the formation of a ternary complex between RBM39 and the E3 ubiquitin ligase CUL4-DCAF15, resulting in the proteasomal degradation of RBM39. CB039 holds promise for research into cancers dependent on RBM39, such as acute myeloid leukemia (AML) and ovarian cancer.
Smiles
N(S(=O)(=O)C1=CC(NC(C(=O)N2[C@@H](CO)CCC2)=O)=CC=C1)C3=C4C(C(C#N)=CN4)=C(C)C=C3
Molecular Formula
C23H23N5O5S
Molecular Weight
481.524
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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