RIPK1-IN-29
Product Specifications
Target
RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
RIPK1-IN-29 (Compound 22) is a RIPK1 inhibitor with an IC50 of 6.9 nM. It exhibits anti-necroptotic apoptosis activity by inhibiting RIPK1. In a TNF-α induced inflammatory in vivo model, a 10 mg/kg dose of RIPK1-IN-29 can protect mice from hypothermia and death. This compound is suitable for research in the field of inflammatory diseases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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