What is the catalog number for EGFR-IN-159?

The catalog number for EGFR-IN-159 is T206989.

What sizes are available for EGFR-IN-159?

EGFR-IN-159 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR-IN-159 come in?

EGFR-IN-159 is available in 2 different pack sizes.

Is EGFR-IN-159 in stock?

EGFR-IN-159 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR-IN-159?

EGFR-IN-159 is manufactured by Molfinity.

What is the estimated delivery time for EGFR-IN-159?

Estimated delivery time for EGFR-IN-159 is approximately 10 business day(s), depending on your location.

EGFR-IN-159

Product Specifications

CAS Number

2055746-08-0

Target

EGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Bioactivity

EGFR-IN-159 (compound 12) is a dihydropyrimidine and a potent EGFR inhibitor with an IC50 of 29.00 nM. It exhibits dose-dependent inhibition of EGFR and HER2. The compound shows cytotoxicity against MCF-7 breast cancer cells and Vero cells with IC50 values of 16.07 μg/mL and 35.98 μg/mL, respectively. EGFR-IN-159 does not cross the blood-brain barrier (BBB) and demonstrates significant anticancer activity.