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G-6599

Product Specifications

CAS Number

2901806-51-5

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Bioactivity

G-6599 is a monovalent degrader targeting SMARCA2/A4, with DC50 values of 0.018 nM and 0.056 nM, respectively. It demonstrates degradation activity and antiproliferative effects in AR-dependent prostate cancer cell lines.

Smiles

OC1=CC=CC=C1C=2N=NC(N)=C(C2)N3CC4N(C=5C=CN=C(C#CCCN6CCCCCC6)C5)C(C3)CC4

Molecular Formula

C31H37N7O

Molecular Weight

523.672

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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