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EN1441

Product Specifications

CAS Number

2196448-47-0

Target

Androgen Receptor

Related Pathways

Endocrinology/Hormones

Bioactivity

EN1441 is a covalent degrader that targets the androgen receptor (AR) with an EC50 value of 4.2 ?M, as well as its truncated variant AR-V7. It selectively and effectively degrades AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 holds potential for research into androgen-independent prostate cancer.

Smiles

O=C(C=C)N1C2=CC(Cl)=CC=C2NC(=O)C1(C)C

Molecular Formula

C13H13ClN2O2

Molecular Weight

264.708

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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