PROTAC KDM4 degrader-1
Product Specifications
Target
Apoptosis, PROTACs, Histone Demethylase
Related Pathways
Chromatin/Epigenetic, Apoptosis, PROTAC
Bioactivity
PROTACKDM4 degrader-1 (Compound 11) is a proteolysis-targeting chimera (PROTAC) degrader specifically designed for KDM4. It effectively degrades KDM4A-C while sparing KDM4D. In esophageal cancer cells, PROTACKDM4 degrader-1 demonstrates strong antiproliferative activity, inducing apoptosis and cell cycle arrest, and inhibits lysine demethylation of histone H3.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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