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BRD4 degrader-6

Product Specifications

CAS Number

3055207-38-7

Target

Epigenetic Reader Domain, PROTACs

Related Pathways

PROTAC, Chromatin/Epigenetic

Bioactivity

BRD4 degrader-6 is a dimeric BDR4PROTAC class degrader with a DC50 of less than 0.1 μM. It effectively induces the ubiquitination and degradation of BDR4, exhibiting anticancer properties.

Smiles

C(CNC(C[C@H]1C=2N(C3=C(C(=N1)C4=CC=C(Cl)C=C4)C(C)=C(C)S3)C(C)=NN2)=O)[C@]56[C@](C[C@@]7(C(C)(C)[C@]5(C7)[H])[H])(OB(O6)C8=C(CCC(N[C@H](C(=O)N9[C@H](C(NCC%10=CC=C(C=C%10)C%11=C(C)N=CS%11)=O)C[C@@H](O)C9)C(C)(C)C)=O)C=CC=C8)[H]

Molecular Formula

C61H71BClN9O7S2

Molecular Weight

1152.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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