Tetrafluoro-thalidomide
Product Specifications
CAS Number
179033-21-7
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
Tetrafluoro-thalidomide is a fluorinated analog of thalidomide. It acts as an activator of E3 ligase enzymes, facilitating the ubiquitination of proteins for subsequent proteolysis. The structure of tetrafluoro-thalidomide can be further derivatized through fluorine substitution.
Smiles
O=C1C=2C(F)=C(F)C(F)=C(F)C2C(=O)N1C3C(=O)NC(=O)CC3
Molecular Formula
C13H6F4N2O4
Molecular Weight
330.191
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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