AX-53802
Product Specifications
CAS Number
1008482-71-0
Target
Ferroptosis, Glutathione Peroxidase
Related Pathways
Apoptosis, Metabolism
Bioactivity
AX-53802 is a ferroptosis (ferroptosis) inducer targeting GPX4, with an IC50 of 0.34 μM. It forms a covalent bond with GPX4, initiating membrane translocation upon binding. In combination with FAK/Src inhibitors, AX-53802 enhances cell death. This compound is applicable in cancer research.
Smiles
O=C(C#C)N(C1=CC=C2OCOC2=C1)C(C(=O)NC3CCCC3)C=4C=CC=CC4F
Molecular Formula
C23H21FN2O4
Molecular Weight
408.422
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARO-A15272-01 50 µg
Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (B11)
Sign In for Pricing
View Details ARO-A15272-02 100 µg
Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (B11)
Sign In for Pricing
View Details ARO-A15272-03 1 mg
Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (B11)
Sign In for Pricing
View Details MBS8425889-01 1 Kit
Human S100 Calcium Binding Protein A12 CLIA Kit
Sign In for Pricing
View Details