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HW161023

Product Specifications

CAS Number

2920698-73-1

Target

AAK1, AAK1 (AP2 associated kinase 1)

Related Pathways

Neuroscience

Bioactivity

HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.

Smiles

O(C[C@@](CC(C)C)(C)N)C=1N2C(C(=CC1)C=3C=C(C(F)F)N=CC3)=NC=C2

Molecular Formula

C20H24F2N4O

Molecular Weight

374.428

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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