HW161023
Product Specifications
CAS Number
2920698-73-1
Target
AAK1|||AAK1 (AP2 associated kinase 1)
Related Pathways
Neuroscience
Bioactivity
HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 ?M for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.
Smiles
O(C[C@@](CC(C)C)(C)N)C=1N2C(C(=CC1)C=3C=C(C(F)F)N=CC3)=NC=C2
Molecular Formula
C20H24F2N4O
Molecular Weight
374.428
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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