Rhodblock 1a
Product Specifications
CAS Number
701226-08-6
Target
ROCK
Related Pathways
Stem Cells|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling
Bioactivity
Rhodblock 1a is an inhibitor of the Rho kinase signaling pathway, which disrupts the localization and function of proteins within the Rho pathway. This interference hinders the proper formation of the cleavage furrow during cell division, leading to some cells either failing to form the cleavage furrow or forming a ruptured furrow, resulting in binucleated cells. Rhodblock 1a can be utilized for investigating cell division mechanisms and holds potential for research into cardiovascular diseases and cancer.
Smiles
O=C(C=1OC=CC1)N2N=C(C=3C=CC=CC3)CC2C=4C=CC=CC4
Molecular Formula
C20H16N2O2
Molecular Weight
316.353
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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