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PARP1/CDK12-IN-1

Product Specifications

Target

PARP, CDK

Related Pathways

Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

PARP1/CDK12-IN-1 (107) is a dual inhibitor that targets both CDK12 and PARP1, exhibiting IC50 values of 285 nM and 34 nM, respectively.

Smiles

O=C(N)C1=C(N=C(NC(C2=CC(C(N3CCC(NC4=NC=C(I)N=C4)CC3)=O)=CC=C2)=O)N5)C5=CC=C1

Molecular Formula

C25H23IN8O3

Molecular Weight

610.406

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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