PI3K-IN-56
Product Specifications
CAS Number
2633645-58-4
Target
Akt, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Bioactivity
PI3K-IN-56 (Compound 1) is an orally active, potent, and selective irreversible inhibitor of phosphoinositide 3-kinase (PI3K) . It irreversibly blocks the production of phosphatidylinositol-3,4,5-trisphosphate (PIP3) and the downstream AKT signaling pathway. PI3K-IN-56 holds promise for research in PI3Kα-driven cancers, such as breast and ovarian cancer.
Smiles
O=C(OC)NC=1N=CC(C=2N=C(C3=CC(=CN3N2)CN4CCN(C(=O)CNC(=O)C=C)CC4)N5CCOCC5)=C(C1)C(F)(F)F
Molecular Formula
C28H32F3N9O5
Molecular Weight
631.606
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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