What is the catalog number for TGFβRI-IN-7?

The catalog number for TGFβRI-IN-7 is T206870.

What sizes are available for TGFβRI-IN-7?

TGFβRI-IN-7 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does TGFβRI-IN-7 come in?

TGFβRI-IN-7 is available in 2 different pack sizes.

Is TGFβRI-IN-7 in stock?

TGFβRI-IN-7 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TGFβRI-IN-7?

TGFβRI-IN-7 is manufactured by Molfinity.

What is the estimated delivery time for TGFβRI-IN-7?

Estimated delivery time for TGFβRI-IN-7 is approximately 10 business day(s), depending on your location.

TGFβRI-IN-7

Product Specifications

Target

TGF-beta/Smad

Related Pathways

Stem Cells

Bioactivity

TGFβRI-IN-7 (compound 16W) is a potent inhibitor of TGFβRI. It effectively inhibits the phosphorylation of SMAD2/3 and reduces the viability of H22 cells, with IC50 values of 12 nM and 65 nM, respectively. In an H22 cell xenograft model, TGFβRI-IN-7 exhibits antitumor efficacy with a TGI of 79.6%.