P5 (PEG12) -VC-PAB-Exatecan
Product Specifications
CAS Number
2928571-52-0
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
P5 (PEG12) -VC-PAB-Exatecan (LP3) is an integral part of a drug-linker conjugate for ADC, formed by linking P5 (PEG24) -VC-PAB with the DNA topoisomerase I inhibitor, Exatecan. It is utilized in the preparation of antibody-drug conjugates (ADC) and employed in tumor research.
Smiles
N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(=O)C2=CC=C(NP(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)(C#C)=O)C=C2)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
Molecular Formula
C76H103FN9O24P
Molecular Weight
1576.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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