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P5 (PEG12) -VC-PAB-Exatecan

Product Specifications

CAS Number

2928571-52-0

Target

Drug-Linker Conjugates for ADC, Topoisomerase

Related Pathways

DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

Bioactivity

P5 (PEG12) -VC-PAB-Exatecan (LP3) is an integral part of a drug-linker conjugate for ADC, formed by linking P5 (PEG24) -VC-PAB with the DNA topoisomerase I inhibitor, Exatecan. It is utilized in the preparation of antibody-drug conjugates (ADC) and employed in tumor research.

Smiles

N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(=O)C2=CC=C(NP(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)(C#C)=O)C=C2)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

Molecular Formula

C76H103FN9O24P

Molecular Weight

1576.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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