BET-IN-28
Product Specifications
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
BET-IN-28 (Compound 44) is a potent inhibitor of bromodomain and extra-terminal domain (BET) proteins, exhibiting an IC50 value of 4.47 nM for BRD4-BD1. It obstructs the interaction between BET proteins and the N-acetylated lysine residues on histone tails, leading to the downregulation of specific gene expression. BET-IN-28 is applicable in research related to hematologic malignancies and solid tumors.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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