MNN-02-155
Product Specifications
CAS Number
3067681-22-2
Target
Histone Acetyltransferase, Bcl-6, Molecular Glues
Related Pathways
Chromatin/Epigenetic, PROTAC, Immunology/Inflammation
Bioactivity
MNN-02-155 is a bivalent molecular glue that can simultaneously interact with both p300/CBP and BCL6. It effectively induces the activation of BCL6-targeted reporter genes and promotes cell death. This compound is used in the research of diffuse large B-cell lymphoma (DLBCL) .
Smiles
O=C(NC)N1CC=2C(=NN(C2CC1)C3CCN(C(=O)CCCCNC(=O)C4CCN(C5=NC=C(Cl)C(=N5)NC=6C=C(OC)C7=C(C=C(OCC(=O)NC)C(=O)N7C)C6)CC4)CC3)N8C=9C=C(C(=CC9CCC8)C=%10C=NN(C%10)C)C(F)F
Molecular Formula
C56H68ClF2N15O7
Molecular Weight
1136.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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