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HRG038

Product Specifications

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Bioactivity

HRG038 is a selective covalent BRD4 degrader. It binds covalently to the E3 ubiquitin ligase CUL4 DCAF16, recruiting it to BRD4, which results in BRD4 ubiquitination and subsequent proteasomal degradation. HRG038 holds potential for cancer research.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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