BNS808
Product Specifications
CAS Number
2836313-12-1
Target
Cytochromes P450, Cannabinoid Receptor
Related Pathways
Metabolism, GPCR/G Protein
Bioactivity
BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD) . BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.
Smiles
O=S(=O)(NC1C2=NN(C=3C=CC=CC3Cl)C(C=4C=CC(Cl)=CC4)=C2OCCC1)C5=CC=C(Cl)C=C5
Molecular Formula
C25H20Cl3N3O3S
Molecular Weight
548.869
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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