KRAS inhibitor-41
Product Specifications
CAS Number
3056974-50-3
Target
Ras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
KRAS inhibitor-41 is a KRAS inhibitor with an IC50 value of less than 0.01 μM for both KRAS G12D and KRAS G12V mutations. It effectively inhibits RAS mutant cell lines GP2D (KRAS-G12D) and SW620 (KRAS-G12V) . KRAS inhibitor-41 is applicable for cancer research.
Smiles
C(#N)C=1C=2C3(CN(C3)C=4N=C(N([C@H](C)C5=C(N)N=CC=C5)CC)N=C(OC[C@@]67N(C[C@H](F)C6)CCC7)N4)CCC2SC1N
Molecular Formula
C30H37FN10OS
Molecular Weight
604.745
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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