P2Y14R antagonist 4
Product Specifications
CAS Number
3081687-67-1
Target
P2Y Receptor|||Interleukin
Related Pathways
Immunology/Inflammation|||Neuroscience|||GPCR/G Protein
Bioactivity
Compound 25l, also known as P2Y14R antagonist 4, is an orally active antagonist of the P2Y14R receptor with an IC50 of 5.6 nM. It exhibits higher binding affinity for P2Y14R compared to other PPTN receptors. P2Y14R antagonist 4 also possesses anti-inflammatory properties, reducing the release of pro-inflammatory cytokines (IL-1?, IL-6, and TNF-?) induced by LPS.
Smiles
O=C(O)C1=CC(=CC(=C1)C2=CC=C(C=C2)C3CCNCC3)NS(=O)(=O)CCC4=CC=C(C=C4)C(F)(F)F
Molecular Formula
C27H27F3N2O4S
Molecular Weight
532.574
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15241514 1 Vial
Lentiviral mouse Hk1 shRNA (UAS) - Lentiviral mouse Hk1 shRNA (UAS, iRFP) (25)
Ask
View Details 
N7100-66A-HRP 100 µL
NME1 (Nucleoside Diphosphate Kinase A, NDP Kinase A, NDK A, Tumor Metastatic Process-Associated Protein, Metastasis Inhibition Factor nm23, nm23-H1, Granzyme A-Activated DNase, GAAD, NDPKA, NM23) (Azide Free) (HRP)
Ask
View Details 
A1125-11B-PE 200 µL
AKT1, phosphorylated (Ser129) (RAC-alpha Serine/Threonine-protein Kinase, RAC-PK-alpha, Protein Kinase B, PKB, Proto-oncogene c-Akt, PKB, RAC) (PE) discontinued
Ask
View Details MBS1288956-01 0.02 mg (E-Coli)
Recombinant Bacillus clausii UPF0061 protein ABC1129 (ABC1129)
Ask
View Details MBS1288956-02 0.02 mg (Yeast)
Recombinant Bacillus clausii UPF0061 protein ABC1129 (ABC1129)
Ask
View Details