RSK-IN-2
Product Specifications
CAS Number
3011713-80-4
Target
Apoptosis|||S6 Kinase
Related Pathways
PI3K/Akt/mTOR signaling|||Apoptosis|||MAPK
Bioactivity
RSK-IN-2 (Compound 3e) is an inhibitor of RSK, showing IC50 values of 37.89 nM for RSK2, 30.78 nM for RSK1, 20.51 nM for RSK3, and 91.28 nM for RSK4. It suppresses tumor cell proliferation, induces apoptosis, and causes cell cycle arrest at the G2/M phase.
Smiles
O=C(NCCO)C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCN(C)CC4
Molecular Formula
C25H30ClN7O3
Molecular Weight
512.004
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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