Anticancer agent 271
Product Specifications
Target
MTOR, EGFR, PI3K
Related Pathways
Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, JAK/STAT signaling, Angiogenesis
Bioactivity
Anticanceragent 271 (compound 5C) exhibits antiproliferative activity against lung cancer (A549), colon cancer (Caco-2) cell lines, and human lung fibroblasts (WI38), with an IC50 value of 9.18 μM for A549 cells. This compound can downregulate PI3K and mTOR gene expression and is applicable in cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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