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Anticancer agent 271

Product Specifications

Target

MTOR, EGFR, PI3K

Related Pathways

Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, JAK/STAT signaling, Angiogenesis

Bioactivity

Anticanceragent 271 (compound 5C) exhibits antiproliferative activity against lung cancer (A549), colon cancer (Caco-2) cell lines, and human lung fibroblasts (WI38), with an IC50 value of 9.18 μM for A549 cells. This compound can downregulate PI3K and mTOR gene expression and is applicable in cancer research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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