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MAT2A-IN-24

Product Specifications

CAS Number

3031093-57-6

Target

Methionine Adenosyltransferase (MAT)

Related Pathways

Chromatin/Epigenetic

Bioactivity

MAT2A-IN-24 (Compound 9) is an inhibitor of methionine adenosyltransferase 2a (MAT2a), with an IC50 value of 20 nM for MAT2a inhibition and an antiproliferative IC50 value of 10 nM for HAP1MTAP–/– cells. MAT2A-IN-24 is applicable in the research of tumor diseases associated with MTAP deficiency.

Smiles

O=C1N=C(C=2C=CC(Cl)=CC2N1C3=CC=CC(=C3)N4CCC(CN5C(=O)N=C(C=6C=CC(Cl)=CC65)N(C)C)CC4)N(C)C

Molecular Formula

C32H33Cl2N7O2

Molecular Weight

618.556

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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