MAT2A-IN-24
Product Specifications
CAS Number
3031093-57-6
Target
Methionine Adenosyltransferase (MAT)
Related Pathways
Chromatin/Epigenetic
Bioactivity
MAT2A-IN-24 (Compound 9) is an inhibitor of methionine adenosyltransferase 2a (MAT2a), with an IC50 value of 20 nM for MAT2a inhibition and an antiproliferative IC50 value of 10 nM for HAP1MTAP–/– cells. MAT2A-IN-24 is applicable in the research of tumor diseases associated with MTAP deficiency.
Smiles
O=C1N=C(C=2C=CC(Cl)=CC2N1C3=CC=CC(=C3)N4CCC(CN5C(=O)N=C(C=6C=CC(Cl)=CC65)N(C)C)CC4)N(C)C
Molecular Formula
C32H33Cl2N7O2
Molecular Weight
618.556
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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