What is the catalog number for NLRP3-IN-76?

The catalog number for NLRP3-IN-76 is T206713.

What sizes are available for NLRP3-IN-76?

NLRP3-IN-76 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does NLRP3-IN-76 come in?

NLRP3-IN-76 is available in 2 different pack sizes.

Is NLRP3-IN-76 in stock?

NLRP3-IN-76 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NLRP3-IN-76?

NLRP3-IN-76 is manufactured by Molfinity.

What is the estimated delivery time for NLRP3-IN-76?

Estimated delivery time for NLRP3-IN-76 is approximately 10 business day(s), depending on your location.

NLRP3-IN-76

Product Specifications

Target

Interleukin, NF-κB, NOD-like Receptor (NLR), NO Synthase

Related Pathways

Immunology/Inflammation, NF-κB

Bioactivity

NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα) . It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD) .