PCSK9 autophagic degrader 2
Product Specifications
CAS Number
2974497-11-3
Target
ATTECs
Related Pathways
PROTAC
Bioactivity
PCSK9 autophagic degrader 2 (W6) is an autophagosome-targeting agent for PCSK9, with a DC50 value of 20.6 nM. It exhibits effects comparable to anti-atherosclerotic treatments and has a binding constant (KD) with LC3B of 2.5 μM.
Smiles
O=C1C(=CC2=CC(Br)=C(O)C(Br)=C2)C3=CC(I)=CC=C3N1CCOCCOCCOCCOC=4C=C5C(=CC4OC)CCNC5(C)CC(=O)NC6=NC=CS6
Molecular Formula
C39H41Br2IN4O8S
Molecular Weight
1012.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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