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GHSR-1a agonist-1

Product Specifications

CAS Number

3060887-25-1

Target

GHSR

Related Pathways

GPCR/G Protein

Bioactivity

GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a) with an EC50 of 0.49 nM. It effectively stimulates the release of endogenous growth hormone by activating GHSR-1a. Doses as low as 0.1 mg/kg (administered orally) can increase body weight and length in 4-week-old rats. GHSR-1a agonist-1 is applicable in research on pediatric growth and developmental delays.

Smiles

C([C@@]12C(=NN(C1=O)C3CC3)CCN(C([C@H](NC(C(C)(C)N)=O)COCC4=CC=CC=C4)=O)C2)C5=CC=CC=C5

Molecular Formula

C30H37N5O4

Molecular Weight

531.646

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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