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PROTAC SMARCA2/4 degrader-38

Product Specifications

Target

Epigenetic Reader Domain, PROTACs, Apoptosis

Related Pathways

PROTAC, Chromatin/Epigenetic, Apoptosis

Bioactivity

PROTACSMARCA2/4 degrader-38 is a SMARCA2/4 PROTAC degrader with DC50 values of 3.0 nM and 4.0 nM, respectively. It facilitates the ubiquitination and degradation of SMARCA2/4 and can block the G0/G1 phase of the cell cycle, leading to the induction of apoptosis. PROTACSMARCA2/4 degrader-38 is applicable in acute myeloid leukemia (AML) research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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