PROTAC SMARCA2/4 degrader-38
Product Specifications
Target
Epigenetic Reader Domain|||PROTACs|||Apoptosis
Related Pathways
PROTAC|||Chromatin/Epigenetic|||Apoptosis
Bioactivity
PROTACSMARCA2/4 degrader-38 is a SMARCA2/4 PROTAC degrader with DC50 values of 3.0 nM and 4.0 nM, respectively. It facilitates the ubiquitination and degradation of SMARCA2/4 and can block the G0/G1 phase of the cell cycle, leading to the induction of apoptosis. PROTACSMARCA2/4 degrader-38 is applicable in acute myeloid leukemia (AML) research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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