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PARP7-IN-24

Product Specifications

CAS Number

3072866-54-4

Target

PARP

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

PARP7-IN-24 (compound 44) is a potent inhibitor of PARP7, demonstrating an EC50 of 0.375 nM for pSTAT1 in NCI-H1373 cells. It shows potential for use in cancer research.

Smiles

O=C1C=2C(=CC(=C(F)C2F)C=3N=CC(OC)=CN3)C=CN1C[C@@H](C[C@@H](OC4=C(C(F)(F)F)C(=O)NN=C4)C)F

Molecular Formula

C24H19F6N5O4

Molecular Weight

555.429

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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