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UNC9426

Product Specifications

CAS Number

3051784-94-9

Target

Platelet aggregation, TAM Receptor

Related Pathways

Others, Tyrosine Kinase/Adaptors

Purity

0.98051

Bioactivity

UNC9426 is an orally active, potent and selective TYRO3 inhibitor with an IC50 of 2.1 nM. It reduces platelet aggregation without prolonging bleeding time and blocks TYRO3-dependent functions in tumour cells and macrophages, making it suitable for studying thrombosis and platelet aggregation.

Smiles

N(C=1N=C2C(C(=CN2[C@H]3CC[C@H](O)CC3)C4=CC=C(CN5CCN(C)CC5)C=C4)=CN1)C6=CC(C(F)(F)F)=CC(C(F)(F)F)=C6

Molecular Formula

C32H34F6N6O

Molecular Weight

632.642

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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