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TYK2 ligand 2

Product Specifications

CAS Number

2924460-80-8

Target

JAK

Related Pathways

JAK/STAT signaling, Chromatin/Epigenetic, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.

Smiles

O=C(O)C1=CN=C(C=C1)NC2=NC=C(C(=O)NC)C(=C2)NC3=CC=CC(C4=NC=C(F)C=N4)=C3OC

Molecular Formula

C24H20FN7O4

Molecular Weight

489.458

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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