SOF-436
Product Specifications
CAS Number
2224491-20-5
Target
Ras
Related Pathways
GPCR/G Protein|||MAPK
Bioactivity
SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 ?M) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.
Smiles
O=S(=O)(F)C1=CC=CC(=C1)S(=O)(=O)NC2=CC=C(C(F)=C2)C3CC3
Molecular Formula
C15H13F2NO4S2
Molecular Weight
373.395
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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