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LSD1-IN-42

Product Specifications

Target

Histone Demethylase, PD-1/PD-L1

Related Pathways

Chromatin/Epigenetic, Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint

Bioactivity

LSD1-IN-42 (Compound 7ae) is an orally active LSD1 inhibitor that significantly suppresses LSD1 activity (IC50 = 0.08 μM) . It reduces PD-L1 expression and enhances the tumor-killing effect of T cells. LSD1-IN-42 demonstrates notable anti-gastric cancer activity by inhibiting tumor cell invasion and migration.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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