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SIK2/3-IN-1

Product Specifications

CAS Number

3038863-24-7

Target

SIK

Related Pathways

PI3K/Akt/mTOR signaling

Bioactivity

SIK2/3-IN-1 (Compound 7S) is an orally active and selective inhibitor of SIK2/3. It significantly inhibits tumor growth without causing weight loss in the MV4-11 AML mouse CDX model. SIK2/3-IN-1 is applicable for research in MEF2C-dependent acute myeloid leukemia.

Smiles

O=C1C=2C(=NC(=CC2CCN1CC(F)(F)F)C=3C=C(C=NC3N)C=4C=NN(C4)C)OC

Molecular Formula

C20H19F3N6O2

Molecular Weight

432.399

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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